The major goals of the Family Investigation of Nephropathy and Diabetes (FIND) study are to acquire sets of families as well as case-control sets with well-characterized diabetic nephropathy, establish a secure master database, and to localize and identify genes that influence susceptibility to diabetic nephropathy and end stage renal disease. FIND recruits European American (EA), African American (AA), Mexican American (MA) and American Indian (AI) populations to assess genetic contributions that may be specific to various populations. Genetic strategies include genome-wide linkage analyses and Mapping by Admixture Linkage Disequilibrium (MALD). In addition, most of the clinical centers conduct a separate sub-study for diabetic retinopathy.
Enrollment of new families for the genome-wide linkage analyses is closed as of 2005. Enrollment of AA and MA case control sets is still open to recruitment through February 2007.
CLICK HERE for more information about recruitment.
CLICK HERE for a list of FIND principal investigators.
CLICK HERE for access to the FIND Collection Website.